AMP: 8 Location: Greeley Hwy and I-80, Cheyenne Turn right for I-80 east. Stay straight for I-80 west. The stretch of US 85 from here to downtown runs concurrent with I-180, a fully non freeway interstate highway. The designation really shouldn’t exist especially since it is entirely superfluous and signs along I-80 and I-25 point … Continue reading U.S. Route 85, WYO 221 to I-80/I-180